
Biomanufacturing is advancing at a remarkable pace, but media development hasn’t kept up. Most cells are still grown in formulations designed 60+ years ago, and traditional methods can’t navigate the sheer complexity of media design, where dozens of interacting ingredients must be fine-tuned to unlock meaningful performance gains. As a result, companies across biologics, advanced therapies, and cellular agriculture are held back by media that is slow, expensive, and under-optimized.
Multus exists to change that. Our MediOP™ platform brings together AI, high-throughput robotics, and deep cell biology expertise to deliver cell-specific media in months, not years. We turn media from a bottleneck into an engine for performance, yield, and scale.
Despite rapid progress across cell engineering, bioprocessing, and automation, most media formulations in use today still trace back decades. This isn’t because the field hasn’t tried to innovate - it’s because media is uniquely difficult to optimize. With multiple interacting ingredients, each with many potential concentrations, the design space quickly becomes enormous. Even with best-practice methods, fine-tuning media remains one of the hardest challenges in biomanufacturing.
Teams have relied on well-established tools - OFAT, DoE, blending, SMA, Omics, simulation, and deep expertise - because they are proven, practical, and accessible. Each brings strengths and has driven meaningful insights across the industry. However, these approaches are not suited to capture or analyze the volume of empirical data required to fully map how ingredients interact at scale. As a result, even well-run optimization campaigns tend to explore only a small fraction of what’s possible.
This has created industry complacency: media is often treated as “good enough,” even though meaningful gains in growth, yield, cost, or consistency are still waiting to be unlocked. The barrier is a lack of infrastructure to generate, integrate, and interpret sufficient data.
That's where our approach comes in. MediOP™ gives teams access to a level of experimental throughput and statistical power that simply wasn’t feasible before. This means we can uncover improvements that traditional campaigns can’t easily reach - not because those methods are flawed, but because media design demands a depth of exploration that only automated, iterative data generation can support.
MediOP™ is a fully integrated, data-driven media design platform that combines:
All data generated in our facility is fed back into our models, making MediOP™ more powerful with each experiment. This means we now own the world’s largest structured dataset on media performance, which enables performance gains that conventional approaches simply cannot match.
MediOP™ is built to be flexible - whether you’re validating a new cell line, intensifying a mature process, or starting from scratch. That same flexibility also enables us to work with black-box ingredients and redacted baseline formulations, ensuring your IP remains fully protected while you access the power of our platform.
Every team is at a different stage - validating cell lines, planning scale-up, or troubleshooting a stubborn yield ceiling. Our service models are intentionally modular so you can work with us in the way that fits your needs, timelines, and strategic goals.
For when you need media today.
Our catalog includes ready-made, animal-component-free formulations for specific cell types, derived from our data-driven process. The turnaround is immediate, and you get off-the-shelf media, technical documentation, and customer support.
For when you need better media quickly.
Express screens our existing, data-rich formulation libraries to predict better-performing media for your cells. It's perfect for organizations seeking a quick and cost-effective performance uplift without committing to a full optimization program. The turnaround is 1-3 months, and you get 1-3 formulations ready for testing.
For when you want more from your media.
If you have a proven baseline formulation that still leaves yield or consistency on the table, Boost can take you further. MediOP™ identifies enhancements without needing to know the content of your proprietary formulation. The turnaround is 3-6 months, and you get 3-5 optimized candidate formulations, along with regular progress reports.
For when you need a custom formulation from scratch.
If you can’t find a suitable media solution, we can design new media with up to 100 ingredients, tailored to your specific cells, process, and commercial constraints, through multiple MediOP™ iterations. This is a great solution for cell therapy companies seeking an FBS- or hPL-free solution, biologics teams needing media tuned to a specific product, or cultivated meat companies working with especially challenging cell types that aren’t supported by standard media. The turnaround is 6-9 months, and you’ll receive 5-10 validated candidate formulations alongside monthly progress reports.
Whether you need a quick performance boost or a fully customized formulation built for long-term manufacturing, Multus delivers media designed for your cells’ potential.
No other platform combines automated data generation, AI-driven insights, and deep cell biology to design media this fast, this targeted, and this reliable.
Ready to unlock the full potential of your cells? Contact our media specialists, who are here to help you choose the right service and get started.
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